Investigation of Antimicrobial Susceptibilities Among Bacteria Isolated from Blood Cultures in Hospitalized Patients, Tehran, Iran

Background: Bacteremia is the status, which detected via a positive blood culture test with no contamination. Centers for Disease Control and Prevention (CDC) indicates that direct medical procedures total costs are significantly high. Antibiotic resistance can play major role in costs, related to long duration of treatment. Objectives: The aim this study was investigate rate profiles antimicrobial susceptibility isolates from Tehran, Iran. Methods: In current cross-sectional study, 5,000 samples were collected patients hospitalized Loghman General Hospital, Iran, results 2012 2013. Susceptibility agents analyzed using National Committee Clinical Laboratory Standards guidelines. Results: Coagulase-negative staphylococci (38.8%), Staphylococcus aureus (20.5%), Acinetobacter (11.9%), Escherichia coli (11.7%) most frequent bacteria isolated cultures, collectively accounting > 80% isolates. Of microorganisms, 63.75% 36.24% belonged Gram-positive Gram-negative bacteria, respectively. Moreover, 88% MRSA (oxacillin-/methicillin-resistant), 7% VRE (vancomycin-resistant). Conclusions: organisms MDR (multi-drug resistance) obviously indicate misuse antibiotic society. surveillance studies Iran will be useful clinicians choose right empirical treatment help control prevent infections caused by resistant organisms.